Anti-Oxidative Drug Reversed Age-Related Damage to Blood Vessels in Seniors

Anti-aging Drug Added to Skincare Cosmetics

An anti-aging drug that has been added to cosmetics and skin care products has now been shown to be able to reverse age related damage to blood vessels. A New Zealand Kiwi company began marketing in 2013 a super anti-oxidative anti-aging substance called Mitoubiquinone mesylate (MitoQ) as an anti-aging ingredient in skin care products in more than 100 countries. The drug was originally discovered at the University of Otago by Professor Rob Smith and global mitochondria expert Dr. Mike Murphy, of Cambridge University.

MitoQ Improved Oxidative Aging of Blood Vessels 

A new study published April 16, 2018, in the American Heart Association journal Hypertension, suggests that MitoQ can reduce oxidative aging of blood vessels by 15-20 years in only six weeks. Researchers at  the Integrative Physiology of Aging Laboratory at the University of Colorado carried out human trials on MitoQ and the results could prove to be a major breakthrough in preventing coronary heart disease, which is the number one cause of death in the United States.

Heart disease leads to approximately 610,000 deaths every year (one in every four deaths) in the United States. About 735,000 Americans have a heart attack every year (535,000 have a first heart attack and 210,000 have a second or more heart attacks). Coronary artery disease (CAD) is the major cause of heart disease and this is where the arteries are damaged so that blood flow through them is impeded and sometimes cut off which leads to heart attacks.

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Improved Vascular Function and Reduced Stiffness of Aorta

This major anti-oxidant drug MitoQ works by penetrating and improving mitochondria of cells. According to Dr. Mathew Rossman who headed the study, this is the first time that MitoQ was tested on humans. Originally, MitoQ was found successful in improving vascular function and reducing arterial stiffness in mice. Now it has proven to be successful in humans and may pave the way to treating age-related vascular dysfunction, which can increase the life span and the quality of life in humans.

Artery Flow Increased by 42%

Participants in the trial were 20 healthy seniors ages 60-79 who had problems with brachial artery flow. They were given oral supplementation with MitoQ (20 mg/d) or placebo for six weeks in a randomized, placebo-controlled, double-blind, crossover design study. The MitoQ supplement was well tolerated and brachial artery flow increased by 42%. Stiffness of the aorta and plasma levels of oxidized LDL cholesterol were reduced.  In short the damage done to blood vessels due to oxidative stress from aging was reduced considerably.

MitoQ Penetrates Mitochondria of Cells and can Cross Brain Barrier

In the past, many other oral anti-oxidant drugs like Vitamin C and Vitamin E were found by studies to be ineffective and are no longer popular as they once were. These anti oxidants could not penetrate the mitochondria of cells. However, MitoQ which is made from coenzyme Q10 is able to penetrate the mitochondria and it also can cross the brain barrier.

Conclusion

This supplement has the potential to prevent coronary heart disease which is the number one cause of death. This can lead to longer life and a better quality of life.

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